Effects of menthol-induced activation of TRPM8 on heat and cold-evoked potentials

Effects of menthol-induced activation of TRPM8 on heat and cold-evoked potentials - Effects of activation of TRPM8 on heat and cold-evoked potentials

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000047749

Enrollment

Registered

2022-05-13

Start date

2022-05-13

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Healthy college student

Interventions

Application of 10% menthol solution (solvent 2% dimethyl sulfoxide and 88% propylene glycol)

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Healthy adult men and women without skin or brain diseases

Exclusion criteria

Exclusion criteria: Those with a history of skin or brain disease

Design outcomes

Primary

Measure	Time frame
Skin warm and cool sensitivity Skin heat and cold pain sensitivity Heat and cold-evoked potentials Numeric Rating Scale	—

Secondary

Measure	Time frame
Skin temperature	—

Countries

Japan

Contacts

Public ContactTomomi Fujimoto

Niigata University of Health and Welfare Department of Health and Sports

fujimoto@nuhw.ac.jp09085674803

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026