Examination of the effect of ondansetron on the prevention of nausea and vomiting after orthognathic surgery

Examination of the effect of ondansetron on the prevention of nausea and vomiting after orthognathic surgery - Examination of the effect of ondansetron on the prevention of nausea and vomiting after orthognathic surgery

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000047706

Enrollment

Registered

2022-05-11

Start date

2022-05-12

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Patients undergoing orthognathic surgery

Interventions

Administer dexamethasone before surgery and ondansetron at the end of surgery. Administer dexamethasone before surgery and normal saline at the end of surgery.

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Eligible patients meet the criteria of the American Society of Anesthesiologists(ASA) physical status of I-II.

Exclusion criteria

Exclusion criteria: Eligible patients meet the criteria of the American Society of Anesthesiologists(ASA) physical status of 3-5. Patients without consent.

Design outcomes

Primary

Measure	Time frame
Postoperative nausea attitude,Frequency of vomiting (immediately after the end of anesthesia, 2 hours later, 24 hours later)	—

Secondary

Measure	Time frame
Whether to use rescue anti-emetics (metoclopramide)	—

Countries

Japan

Contacts

Public ContactYuna Kang

Tokyo Dental College Dental Anesthesiology

yunakang@tdc.ac.jp03-6380-9001

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026