Development of a new ART technology utilizing cytoplasmic transfer/replacement

Development of a new ART technology utilizing cytoplasmic transfer/replacement - Application of MRT in ART

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

JPRN

Registry ID

JPRN-UMIN000047678

Enrollment

150

Registered

2022-06-01

Start date

2022-06-30

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Infertile couples undergoing ICSI

Interventions

None listed

Eligibility

Sex/Gender

Female

Inclusion criteria

Inclusion criteria: Infertility,Both primary and secondary. No matter what the cause of infertility Age between 20 to 42 is eligible Gender: female who has immature egg

Exclusion criteria

Exclusion criteria: Patient who has infections, such as hepatitis B and C, syphilis, HIV and other virus carrier. Patient who has been registered in other clinical trial In case doctor in charge decided inappropriate.

Design outcomes

Primary

Measure	Time frame
Feasibility of utilization of female genome in 1st polar body of freeze-thaw human eggs in ART by combination of polar body transfer/maternal spindle transfer techniques.	—

Secondary

Measure	Time frame
In vitro development of parthenogenetically activated embryos, ATP and respiratory measurement on developed blastocyst, Spindle morphology and expression of functional proteins.	—

Countries

Japan

Contacts

Public ContactMasahito Tachibana

Tohoku university graduate school of medicine Dept of perinatology

masahito.tachibana.c1@tohoku.ac.jp0227177254

Outcome results