Exploratory study of genome alteration and rearrangement associated with ART (Assisted Reproductive Technology) using birth and three-generation cohort study (TMM BirThree Cohort Study).

Exploratory study of genome alteration and rearrangement associated with ART (Assisted Reproductive Technology) using birth and three-generation cohort study (TMM BirThree Cohort Study). - Exploratory study of genome alteration and rearrangement associated with ART (Assisted Reproductive Technology) using birth and three-generation cohort study (TMM BirThree Cohort Study).

Status

Recruiting

Phases

Unknown

Study type

Observational

Source

JPRN

Registry ID

JPRN-UMIN000047677

Enrollment

3000

Registered

2022-05-10

Start date

2022-05-10

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Birth Children and their family that are classified with conception method, IVF, ICSI and natural conception.

Interventions

None listed

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Participants, birth children and their family, are selected via questionaries of the birth and three-generation cohort study (TMM BirThree Cohort Study) based on conception methods, IVF, ICSI and natural conception. Eligibility is then evaluated via availability of their genome information in the genome reference panels, 54K Japonica Array NEO and jMorp 8.3K JPN, created by Tohoku Medical Megabank project.

Exclusion criteria

Exclusion criteria: Not applicable

Design outcomes

Primary

Measure	Time frame
The frequency of genome alteration and rearrangement, and hereditary, and an association of conception methods, IVF, ICSI and natural conception.	—

Countries

Japan

Contacts

Public ContactJunichi Sugawara

Tohoku Medical Megabank Organization Dept of Community Medical Support

jsugawara@med.tohoku.ac.jp0227236283

Outcome results