Graves'
Conditions
Interventions
None listed
Sponsors
Juntendo University
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: (1) A patient's age at the registration of present study is 20< and <85 years old. (2) A patient with Graves' disease treated only with inorganic iodine (3) Therapeutic dose is less than 25 mg/day as potassium iodine. (4) Thyroid function maintain normal range (>1.0 microIU/mL) at recently more than 2 times. (5) Serum TSH receptor antibody measured by M22 antibody based assay is <10 IU/L. Fulfill the criteria (2)-(5) for more than 6 months before registration. (6) A patient who agrees with the informed consent of present study.
Exclusion criteria
Exclusion criteria: (1) A patient is treated with anti-thyroid drugs except inorganic iodine. (2) A patient is not pregnant woman or lactating woman or expected pregnancy within recent 2 years. (3) A patient has uncontrolled Graves' disease or untreated heart disease. (4) A patient has already treated with radioiodine or surgery. (5) A patient is inappropriate for present study by judging from the manager of the study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Recurrence rate of Graves' hyperthyroidism during and after discontinuation of inorganic iodine treatment | — |
Countries
Japan
Contacts
Public ContactUchida Toyoyoshi
Juntendo University Graduate School of Medicine Department of Metabolism & Endocrinology
Outcome results
None listed