pregnancy
Conditions
Interventions
drawing 10 mL of blood from non-laboring parturients between 37 to 41 weeks of gestation .
For control group, 10 mL of blood is drawn from non-obstetric women.
Sponsors
Juntendo University
Eligibility
Sex/Gender
Female
Inclusion criteria
Inclusion criteria: 1) age 18-45 years old at informed consent 2) diagnosed pregnant and registered for delivery in our hospital(obstetric group) 3) not pregnant and plans gynecological surgery at our hospital (control group) 4) informed and consented to the study
Exclusion criteria
Exclusion criteria: 1)known coagulation abnormality and/or thrombocytopenia < 100 9/L 2) found coagulation abnormality and/or thrombocytopenia < 100 9/L at drawing blood 3) judged improper by the reseacher
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Variables of Quantra Qstat system and correlation between obstetric and non-obstetric patients: clot time(CT), Clot stiffness (CS), platelet contribution to CS (PCS), fibrinogen contribution to CS (FCS), and Clot stability to lysis (CSL) . | — |
Secondary
| Measure | Time frame |
|---|---|
| Correlation with Quantra variables and TEG6s variables and conventional coagulation tests. TEG6s variables: Clotting time (CK R), clot strength value (CRT MA) on the standard citrated kaolin assay, fibrinogen contribution to MA (CFF MA), and fibrinolysis (CRT LY30) . conventional coagulation tests: PT, aPTT, INR, fibrinogen, antithrombin, and fibrin degenerating product. | — |
Countries
Japan
Contacts
Public ContactHisako Okada
Juntendo University Urayasu Hospital Department of Anesthesiology and Pain Medicine
Outcome results
None listed