Effect of Bifidobacterium fermented milk on mother and infant microbiome: sequential observation of gut microbiota during pregnancy and the first two years for infants

nvestigation on the pregnancy and postpartum flora of mothers drinking Bifidobacterium fermented milk and the microbiome of the newborn from birth to 2 years of age - Effect of Bifidobacterium fermented milk on mother and infant microbiota

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000047617

Enrollment

Registered

2022-04-28

Start date

2022-05-01

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Healthy pregnant women and offspring

Interventions

Bifidobacterium fermented milk one bottle per day from 28 weeks to 9 weeks after childbirth

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Japanese pregnant women who are undergoing prenatal checkups at the Research Center for Child Health and Development and are planning to have childbirth and postpartum checkups at this center Pregnant woman who plan vaginal delivery Singleton pregnancy Pregnancy Over 20 years old Pregnant women who understand the research contents, show consent, and can keep the research contents confidential

Exclusion criteria

Exclusion criteria: Pregnant woman with fetal morphological abnormalities Pregnant women with hypertension, diabetes, autoimmune disease, etc.) Pregnant women who will be treated with antibiotics at birth Pregnant women who participate the other innervation (e.g. other functional foods, drugs or cosmetics) during this study period. Pregnant women with milk or gelatin allergies Pregnant women who is not appropriate to participated the study (as judged by the medical doctor)

Design outcomes

Primary

Measure	Time frame
Gut microbiome mother: during pregnancy and after childbirth infants: the first two years	—

Secondary

Measure	Time frame
Vaginal microbiome Gastrointestinal symptoms Intestinal environment (pH, organic acid) Allergies of infant mother: during pregnancy and after childbirth infants: the first two years	—

Countries

Japan

Contacts

Public ContactTomo Suzuki Suzuki

National Center for Child Health and Development Center for Maternal-Fetal, Neonatal and Reproductive Medicine

suzuki-tm@ncchd.go.jp03-3416-0181

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026