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Research of Analysis for Prion and synuclein activity from hair and its roots in patients with rapidly progressive dementia.

Research of Analysis for Prion and synuclein activity from hair and its roots in patients with rapidly progressive dementia. - Research of Analysis for Prion and synuclein activity from hair and its roots in patients with rapidly progressive dementia.

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
JPRN
Registry ID
JPRN-UMIN000047590
Enrollment
500
Registered
2022-04-26
Start date
2021-03-01
Completion date
Unknown
Last updated
2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Rapidly Progressive Dementia Including Prion Disease

Interventions

prion diseases

Sponsors

Nagasaki University
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: (1) Patients visiting the Department of Neurology at each research university between the date of approval by the institutional director of each research center and March 31, 2023. (2) Target diseases: Prion diseases (Creutzfeldt-Jakob disease (CJD), Gerstmann-Streicher-Scheinker syndrome (GSS), fatal familial insomnia (FFI)), epilepsy, neurodegenerative diseases including Alzheimer's disease, rapidly progressive dementia, and healthy subjects (3) Patients who have been fully informed about the participation in this study and who have given their (or their surrogate's) free written consent based on their full understanding of the study. Translated with www.DeepL.com/Translator (free version)

Exclusion criteria

Exclusion criteria: Patients who fall under any one of the following will be excluded from the study. (1) When the research subject and the research subject (or a surrogate) request discontinuation of the study within the period of hospitalization. (2) Other patients deemed inappropriate as research subjects by the investigators, etc.

Design outcomes

Primary

MeasureTime frame
Sensitivity and specificity of prion and synuclein seeding activities from hair and its roots

Secondary

MeasureTime frame
Change in sensitivity from the timing

Countries

Japan

Contacts

Public ContactKatsuya Satoh

Nagasaki University Department of Health Sciences, Unit of Medical and Dental Sciences

satoh-prion@nagasaki-u.ac.jp095-819-7991

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026