Memory improvement by neuro-feedback method targeting sharp wave ripples

Memory improvement by neuro-feedback method targeting sharp wave ripples - Memory improvement by neuro-feedback method targeting sharp wave ripples

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000047589

Enrollment

Registered

2022-04-25

Start date

2022-04-22

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

epilepsy

Interventions

Detect SWR in real-time from the subject&#39

s intracranial EEG. Auditory and visual feedback is presented to the subject based on the detected SWR. Subjects are trained to intentionally control the presented feedback. The experiment will be con

the combined daily training time for A and B is approximately 1 hour. The two feedbacks should be continued if there is no fatigue or other adverse event. If fatigue or other adverse events prevent th

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Patients who have electrodes implanted around the hippocampus for clinical reasons Patients are at least 18 years old but less than 80 years old at the time of consent Patients have given written consent to participate in this study

Exclusion criteria

Exclusion criteria: Patients with significant cognitive impairment Patients deemed unsuitable by the principal investigator or subinvestigator

Design outcomes

Primary

Measure	Time frame
Correct response rate and reaction time of Sternberg memory test before and after neuro-feedback training	—

Secondary

Measure	Time frame
Duration, frequency, and amplitude of detected SWR	—

Countries

Japan

Contacts

Public ContactTakamitsu Iwata

Osaka University Hospital Neurosurgery

t-iwata@nsurg.med.osaka-u.ac.jp0668795111

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026