A study of the therapeutic efficacy of PICSI in patients with repeated miscarriages after embryo transfer and patients with teratozoospermia

A prospective randomized controlled trial of the therapeutic efficacy of PICSI in patients with repeated miscarriage after embryo transfer and patients with teratozoospermia - A study of the therapeutic efficacy of PICSI

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000047539

Enrollment

132

Registered

2022-04-20

Start date

2022-05-09

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Repeated miscarriage patients after embryo transfer, Teratozoospermic patients

Interventions

Sperm selection using hyaluronic acid Sperm selection based on morphology

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Repeated miscarriages or implantation failure after embryo transfer. Teratozoospermic patients. Patients who have given written consent to participate in this study.

Exclusion criteria

Exclusion criteria: Male infertile patients eligible for TESE/TESA/PESA. Patients undergoing ICSI using frozen thawed sperm. Patients who used study reagents within 30 days prior to egg retrieval. Patients who cannot have given written consent to participate in this study.

Design outcomes

Primary

Measure	Time frame
Day3 grade 1 embryo rate	—

Secondary

Measure	Time frame
Fertilization rate, Blastocysto development rate, Clinical pregnancy rate, Abortion rate, HBA score	—

Countries

Japan

Contacts

Public ContactTAKETOSHI KAMIYAMA

Shibakoen Kamiyama Clinic General director

s-kamiyamaclinic@jcom.home.ne.jp0364145641

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026