Healthy adults
Conditions
Interventions
Rinsing oral cavity with mouthwash1 for 30 seconds 3 times a day for 8 weeks.
Rinsing oral cavity with mouthwash2 for 30 seconds 3 times a day for 8 weeks.
Rinsing oral cavity with mouthwash3 for 30 s
Sponsors
Kao Corporation
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: -Male or female of 30 to 59 years of age -Subjects who can come to the test site by their own -Subjects who can sign by their own will -1or2or3 1.Subjects who may bleed from gingival. 2.Subjects with occasional swelling of gingival. 3.Subjects have been diagnosed with swollen gingival or deep periodontal pockets. -Subjects who have 20 or more of their own teeth.
Exclusion criteria
Exclusion criteria: -Subjects with systemic illness. -Subjects who are taking prescription medicine (except for anti-hay fever). -Subjects with a disease in the oral cavity and are consulting the medical institution. -Subjects with periodontal disease is treated -Subjects with the orthodontic therapy. -Subjects with mobile tooth. -Subjects with full denture -Subjects with an implant -Subjects who have regular dental checkups at least 2 times a year. -Subjects who have been prescribed antibiotics for swollen gingival within a year. -The pregnant and subjects who hope to get pregnant during the exam period. -Subjects who usually use gargle. -Subjects with disease in nose -Subjects who dislike perfume, or other odor substances -Subjects who are hypersensitive to chemicals -Subjects with smoking habit -Subjects from outside the company who work in an advertising agency, an investigation, consultancy, mass communication, and the manufacturing industry of health food, cosmetics, toiletries, a sanitary items, and a distributive trade. -Subjects who participate in the other examinations. -Subjects who had health problems (fever, cold-like symptom, abnormal taste or smell, etc.) within 2 weeks prior to the test, or subjects who had a family member living with them who showed abnormalities. -Subjects who had close contact with COVID-19 infected individuals within 2 weeks prior to the study. -Subjects who are confirmed positive in the COVID-19 antigen test on the day of measurement. -Subjects deemed inappropriate to participate in this study by the principle investigator.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Measurement of oral index. Measurements are taken 4 times, before starting test, after using mouthwash for 4 weeks and 8 weeks, and 4 weeks after end of intervention. | — |
Secondary
| Measure | Time frame |
|---|---|
| Intraoral photography, questionnaire and saliva collection are taken 4 times, before starting test, after using mouthwash for 4 weeks and 8 weeks, and 4weeks after end of intervention. Halitosis related measurements, collection of plaque and oral gas are taken 2 times, before starting test and after using mouthwash for 8weeks. | — |
Countries
Japan
Contacts
Public ContactHatsumi Souno
Kao Corporation Biological Science Research
Outcome results
None listed