superficial esophageal cancer
Conditions
Interventions
During mucosal injection in esophageal ESD, use RDI to identify the presence of blood vessels and avoid them during injection.
During mucosal injection in esophageal ESD, white light alone is used for
Sponsors
Keio University
1. National Hospital Organization Tokyo Medical Center 2. Saitama City Hospital
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: Patients over 20 years old who will undergo ESD for lesions diagnosed or suspected to be superficial esophageal cancer at Keio University Hospital and collaborating hospitals. We don't necessarily need a tissue diagnosis.
Exclusion criteria
Exclusion criteria: (1) Cases in which antithrombotic drug withdrawal is not feasible according to guidelines (Guidelines for Gastrointestinal Endoscopy for Patients on Antithrombotic Medications) (2) Lesions less than 5 mm or more than 50 mm in size at the time of preoperative evaluation. (3) Cases in which a histological type other than squamous cell carcinoma, such as Barrett's adenocarcinoma, is suspected. (4) Cases of esophagogastric junction carcinoma in which the resection line does not settle within the squamous epithelium (5) Cases in which the resection is full circumferential (6) Cases after surgical treatment (7) Cases involving scars after endoscopic treatment (8) Cases involving radiotherapy irradiation areas (9) Patients with coagulation disorders (10) Patients on continuous hemodialysis (11) Patients with non-compensated liver cirrhosis (12) Cases that investigators consider inappropriate to conduct this study
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Major bleeding or not | — |
Secondary
| Measure | Time frame |
|---|---|
| 1. The number of blood vessels observed around the lesion 2. Frequency of major/minor bleeding associated with injection 3. The number of hematomas per unit length of the mucosal resection line 4. Procedure time 5. En-block resection rate 6. R0 resection rate 7. Adverse events | — |
Countries
Japan
Contacts
Public ContactKurato Miyazaki
Cancer center Division of research and development for minimally invasive treatment
Outcome results
None listed