pheochromocytoma/paraganglioma(PPGL)
Conditions
Interventions
None listed
Sponsors
Kurume University
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: Select the one that meets all of the following criteria ?Patients aged between 20 and 80 years old ?Patients who have given written consent to participate in the study. However, if you have dementia or mental illness, the patient who obtained the consent of the substitute ?Patients who can or have undergone blood and urinalysis before and after PPGL treatment
Exclusion criteria
Exclusion criteria: Those who meet any of the following criteria are excluded from the target ?Patients with severe renal dysfunction(eGFR <30 mL/min) ?Lactating patients ?Patients judged by the principal investigator and the research coordinator to be inappropriate as research subjects
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Glucose metabolism(fasting blood glucose level,IRI,CPR,HOMA-beta,HOMA-IR)and decreased amount of catecholamines before and after administration of metyrosine. | — |
Secondary
| Measure | Time frame |
|---|---|
| Systolic and diastolic blood pressure and endocrine function (PRL, TSH, FT4, GH, IGF-1, PRA, PAC) before and after administration of metyrosine. Blood pressure fluctuation, blood transfusion volume, urine volume, bleeding volume, phentolamine dose (mg), catecholamine usage before and after surgery. | — |
Countries
Japan
Contacts
Public ContactYuko Matsuo
Kurume University School of Medicine Department of Internal Medicine, Division of Endocrinology and Metabolism
Outcome results
None listed