Elucidation of the molecular pathogenesis of myasthenia gravis using single-cell RNA analysis.

Elucidation of the molecular pathogenesis of myasthenia gravis using single-cell RNA analysis. - Elucidation of the molecular pathogenesis of myasthenia gravis using single-cell RNA analysis.

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

JPRN

Registry ID

JPRN-UMIN000047407

Enrollment

Registered

2022-04-05

Start date

2022-04-05

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Myasthenia gravis

Interventions

None listed

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Acetylcholine receptor antibody positive Patients with generalized myasthenia gravis healthy volunteers

Exclusion criteria

Exclusion criteria: 1) Patients with other autoimmune diseases 2) Patients with carried cancer 3) Persons who have expressed their refusal to participate in this study through a release of information document.

Design outcomes

Primary

Measure	Time frame
Clinical Information for Patients with Myasthenia Gravis Acetylcholine receptor antibody titer Comprehensive RNA expression obtained by single cell RNA sequence Association with TCR and BCR Repatoires	—

Countries

Japan

Contacts

Public ContactHiroyuki Akamine

Chiba University Hospital Department of Neurology

caya3424@chiba-u.jp043-222-7171

Outcome results