Long-term effects of antihypertensive drugs on renal prognosis in patients with hypertensive emergency

Long-term effects of antihypertensive drugs on renal prognosis in patients with hypertensive emergency - Long-term effects of antihypertensive drugs on renal prognosis in patients with hypertensive emergency

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

JPRN

Registry ID

JPRN-UMIN000047340

Enrollment

Registered

2022-04-01

Start date

2021-09-02

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Hypertensive emergency

Interventions

None listed

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: The patients whose systolic or diastolic blood pressure more than 180 or 120 mmHg, respectivel visited the emergency department of Tokyo Bay Urayasu-Ichikawa Medical Center and diagnosed as having heart failure, acute kidney injury, thrombotic microangiopathy, severe hypertensive retinopathy or hypertensive encephalopathy

Exclusion criteria

Exclusion criteria: patients who transferred to other hospitals without admission, 5 patients who required maintenance dialysis therapy upon hospitalization and 14 patients whose renin and aldosterone were not measured during hospitalization

Design outcomes

Primary

Measure	Time frame
The changes in eGFR over 2 years in hypertensive emergency patients	—

Secondary

Measure	Time frame
The ratio of non-dialysis dependence over 2 years in hypertensive emergency patients	—

Countries

Japan

Contacts

Public ContactKeita Endo

Tokyo Bay Urayasu Ichikawa Medical Center Department of Nephrology, Endocrinology and Diabetes

keitaendo78@gmail.com0473513101

Outcome results