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Single Intrasphincteric Injection Of Autologous Adipose-derived Stem Cells To Treat Stress Urinary Incontinence After Radical Prostatectomy: A Pilot Study

Single Intrasphincteric Injection Of Autologous Adipose-derived Stem Cells To Treat Stress Urinary Incontinence After Radical Prostatectomy - SCTTSUI

Status
Active, not recruiting
Phases
Phase 1
Study type
Interventional
Source
JPRN
Registry ID
JPRN-UMIN000047336
Enrollment
10
Registered
2022-03-31
Start date
2019-01-17
Completion date
Unknown
Last updated
2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Stress urinary incontinence after radical prostatectomy

Interventions

treatment group (received a single injection into the urethral rhabdosphincter 10ml of ADSC solution) placebo group (single injection into the urethral rhabdosphincter of 10ml of normal saline).

Sponsors

Al Zahraa Hospital, Beirut, Lebanon
Lead Sponsor

Eligibility

Sex/Gender
Male

Inclusion criteria

Inclusion criteria: patients with an stress urinary incontinence for > 18 months after surgery, localized low to intermediate-risk prostate cancer before surgery, have no biochemical recurrence at study enrollment, the patient had no adjuvant chemotherapy or radiotherapy, all patients had pelvic floor training for > 6 months. All patients had office cystoscopy before entering the study to exclude bladder neck contracture or urethral stenosis

Exclusion criteria

Exclusion criteria: patients taking anticholinergic medications for overactive bladder symptoms or taking a diuretic for heart failure, patients with urinary tract infection, patients with any neurologic disease that may affect bladder function

Design outcomes

Primary

MeasureTime frame
The primary outcomes of our study were the change from baseline in the mean of the 24-h pad weight test.

Countries

Asia(except Japan)

Contacts

Public ContactMohamad Moussa

Lebanese Univeristy Stem Cell Center

mohamadamoussa@hotmail.com+9613964412

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026