Pulmonary arterial hypertension and chronic thromboembolic pulmonary hypertension
Conditions
Interventions
Microcirculatory function of the pulmonary artery is quantified by measurement of hemodynamic variables in the artery with a commercial wire for coronary artery.
Sponsors
Division of Cardiovascular Medicine, Department of Internal Medicine, Kurume University School of Medicine
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: Patients with pulmonary arterial hypertension or chronic thromboembolic pulmonary hypertension in the status of WHO classification: II-III
Exclusion criteria
Exclusion criteria: Patients with allergy to contrast media Patients with bronchial asthma Patients in pregnancy and lactation
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Safety: the presence or absence of injuries of pulmonary arteries during and /or after the catheterization study. Efficacy: symptoms (NYHA functional classification, WHO functional classification, emphasis-10, Specific Activity Scale), 6-minute walk distance 3-12 months after treatment intervention. | — |
Secondary
| Measure | Time frame |
|---|---|
| Serum concentrations of BNP and ureic acid, pulmonary artery pressure, pulmonary artery resistance, cardiac index, index of microvascular resistance, etc. 3-12 months after treatment intervention. | — |
Countries
Japan
Contacts
Public ContactKen-ichiro Sasaki
Kurume University School of Medicine Division of Cardio-Vascular Medicine, Department of Internal Medicine
Outcome results
None listed