Observational study to search for factors that exacerbate the progression and prevention of lifestyle-related diseases through temporal observation of the 75g oral glucose tolerance test, gut microbiota analysis, and metabolites analysis.

Observational study to search for factors that exacerbate the progression and prevention of lifestyle-related diseases through temporal observation of the 75g oral glucose tolerance test, gut microbiota analysis, and metabolites analysis. - Observational study in Kumejima

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

JPRN

Registry ID

JPRN-UMIN000047289

Enrollment

200

Registered

2022-03-26

Start date

2018-12-01

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Metabolic syndrome, obesity, pre diabetes, insulin resistance

Interventions

None listed

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Participants were residents in Kumejima island over 20 years old

Exclusion criteria

Exclusion criteria: 1) severe renal dysfunction (eGFR < 30 ml/min/1.73 m2) 2) hepatic dysfunction (AST > 200 IU/L or ALT > 200 IU/L) 3) malignancy,pregnancy, 4) chronic diarrhea 5) severe illness requiring hospitalization and treatment

Design outcomes

Primary

Measure	Time frame
To search for factors that worsen the progression of lifestyle-related diseases and protective factors through the 75g oral glucose tolerance test, gut microbiota analysis, metabolites analysis, and questionnaire survey observation over time, and to evaluate their significance as early diagnostic markers and predictive markers of pathological progression.	—

Countries

Japan

Contacts

Public ContactTsugumi Uema

Graduate School of Medicine, University of the Ryukyus. Division of Endocrinology, Diabetes and Metabolism,Hematology, Rheumatology.

ma2.ky8.26@gmail.com098-895-1146

Outcome results