Locally recurrent colorectal cancer
Conditions
Interventions
Heavy-ion radiation therapy 73.6Gy/16fr/4weeks
Sponsors
National Institutes for Quantum Science and Technology
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1) Locally recurrent colorectal diseases. 2) Tumor invades or is in close proximity to the gastrointestinal tract, and the site can be observed by colonoscopy. 3) The tumor is not indicated for curative resection. 4) Surgeons at the collaborating institution have previously evaluated that resection of the damaged gastrointestinal tract is feasible. 5) The patient has no distant metastases or has only metastatic lesions that are scheduled for resection. 6) Be at least 20 years of age at the time of enrollment. 7) Patient has a performance status (ECOG) of 0-1. 8) Main organ function is preserved. 9) Written consent for participation in this study has been obtained from the patient.
Exclusion criteria
Exclusion criteria: 1) Patients who are considered to be unable to undergo the prescribed hospital visits and examinations. 2) Patients who are receiving chemotherapy or who have not completed chemotherapy within 2 weeks of the start of irradiation. 3) Patients with open wounds or active, refractory infections in the irradiated area. 4) Patients have active multiple cancers. 5) Patients with serious complications. 6) Patients with mental illness or psychiatric symptoms that would make participation in the clinical research difficult or adults who are incapable of consenting. (7) Patients who are considered to be unsuitable for enrollment in this study by the physician.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The frequency and severity of radiation-induced colitis that occurs within two years after heavy ion therapy | — |
Countries
Japan
Contacts
Public ContactHirotoshi Takiyama
National Institutes for Quantum Science and Technology QST Hospital
Outcome results
None listed