Chronic pain
Conditions
Interventions
None listed
Sponsors
Kansai Medical University
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: Patients with chronic pain that has persisted for at least 3 months since onset (regardless of previous treatment) Patients with a numerical rating scale (NRS) of 6 or higher on a scale of 0 to 10, in addition to the evaluation with the Chronic Pain Acceptance Questionnaire (CPAQ), while already receiving medication as indicated in the Guidelines for the Treatment of Neuropathic Pain.
Exclusion criteria
Exclusion criteria: Those who have difficulty completing the questionnaire Those who have difficulty in continuing treatment for 8 weeks Other persons deemed inappropriate as research subjects by the principal investigator.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Correlation of miRNA expression in neuro-derived exosomes with the rate of change in the catastrophic thinking scale before and after treatment of chronic pain patients across groups. | — |
Secondary
| Measure | Time frame |
|---|---|
| 1) Comparison of miRNA expression in nerve-derived exosomes between a group of healthy subjects without chronic pain and a group of patients with chronic pain 2) Examination of the relationship between clinical assessment measures and exosomal proteins and miRNAs based on omics analysis and pre- and post-treatment correlations of the following items For the clinical evaluation scale, the following items will be calculated from the questionnaire in addition to the basic patient information | — |
Countries
Japan
Contacts
Public ContactTatsuo Nakamoto
Kansai Medical University Hospital Pain center
Outcome results
None listed