The investigation of the relationship between the morphology of coronary atherosclerosis and gene information in coronary artery disease patients.

The investigation of the relationship between the morphology of coronary atherosclerosis and gene information in coronary artery disease patients. - The investigation of the relationship between the morphology of coronary atherosclerosis and gene information in coronary artery disease patients.

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

JPRN

Registry ID

JPRN-UMIN000047125

Enrollment

Registered

2022-05-01

Start date

2022-05-01

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Coronary artery disease patients

Interventions

None listed

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1, Patients of 20 year of age or over 2, Patients who are candidates for DCA 3, Patients for whom written consent has been obtained by the individual

Exclusion criteria

Exclusion criteria: Patients taking steroids or undergoing treatment for cancer, or suffering from hepatitis B and C viruses Other patients who are deemed inappropriate by the physician in charge of the study.

Design outcomes

Primary

Measure	Time frame
The existence of somatic mutation in blood and coronary culprit plaques	—

Secondary

Measure	Time frame
1, The ratio of somatic mutation and the place in gene map of somatic mutation. 2, CT or MRI evaluation of coronary plaques 3, Histological evaluation 4, Single cell RNA and ATAC sequencing of blood and coronary culprit plaque samples 5, The interaction of somatic mutations and single cell RN and ATAC sequencing of blood and coronary culprit plaque samples. 6, Metabolomics in plasma	—

Countries

Japan

Contacts

Public ContactTomoya Yamashita

Kobe University School of Medicine Division of Cardiovascular Medicine, Department of Internal Medicine

tomoya@med.kobe-u.ac.jp078-382-5846

Outcome results