Mild Cognitive Impairment
Conditions
Interventions
Intervention: After the pre-test, the participants participate in a dance program for three months. After completing the dance program, the post-test will conduct.
Control:After the pre-test, the par
Sponsors
Kyoto University
Kyoto Prefectural University of Medicine
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1.A person diagnosed as MCI (memory disorder that is unexplainable by aging and educational level) by a medical doctor in psychiatry or neurology, or a person scored over 24 in MMSE and over 6 in The Lawton Instrumental Activities of Daily Living (IADL) Scale. 2.A person who reports to forget things. 3.A person who is able to go places to test and participate dance classes.
Exclusion criteria
Exclusion criteria: 1.A person who is unsuitable for MRI scan (e.g., having a metallic device in body). 2.A person with a claustrophobia or panic disorder. 3.A left-handed person, or a both-handed person. 4.A person who takes sleeping pills or psychoactive drugs. 5.A person suspected dementia (scored under 23 in MMSE). 6.A person with heart disease. 7.A person who has discovered an aberrant image of the brain that influences cognitive function. 8.A person with a neurological disorder (e.g., parkinsonism) excepted MCI. 9.A person has a medical history of mental disease (e.g., depression).
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| a)Scores of cognitive assessments (Moca and Rivermead Memory Test) measured at pre-test and post-test. b)Oxytocin and 5-HIAA in saliva and urine measured at pre-test and post-test. c)Cerebellar gray matter volume measured at pre-test and post-test. d)Volume of brain activation and functional connectivity during n-back task. | — |
Secondary
| Measure | Time frame |
|---|---|
| a)Correlations between scores of cognitive assessments and subjective wellbeing assessed by psychological scales. b)Correlations between variations of oxytocin,5-HIAA, and cerebellar gray matter volume. c)Correlations between variations of cerebellar gray matter volume and scores of cognitive assessments. d)Correlations between variations of volume of brain activation, brain functional connectivity, and scores of cognitive assessments. e)Correlations between oxytocin, 5-HIAA, volume of brain activation, and brain functional connectivity measured at pre-test. | — |
Countries
Japan
Contacts
Public ContactAya Toyoshima
Shimane University Faculity of Human Sciences
Outcome results
None listed