Analysis of PD-1 and T cells in the pathophysiology of autoimmune thyroid disease and diabetes mellitus

Analysis of PD-1 and T cells in the pathophysiology of autoimmune thyroid disease and diabetes mellitus - PD-1 and T cells in autoimmune thyroid disease and diabetes

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

JPRN

Registry ID

JPRN-UMIN000047092

Enrollment

120

Registered

2022-03-07

Start date

2016-08-26

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

autoimmune thyroid disease and diabetes

Interventions

None listed

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1) Over 15 years old 2) Sex unquestioned 3) The patient who gives a written informed

Exclusion criteria

Exclusion criteria: 1) Patients with a history of immune checkpoint inhibitors 2) Patient with intolerance of medical reasons by doctor

Design outcomes

Primary

Measure	Time frame
PD-1+CD4+Tcell	—

Secondary

Measure	Time frame
PD-1+CD8+Tcell, CD25+FoxP3+Tcell, CD4+Tcell, CD8+Tcell, CD26+CD4+Tcell, CD26+CD3+Tcell, IP-10, TARC, Th1, Th2, sCD26 free T3, free T4, TSH, TRAb, TPOAb, TgAb, WBC, lymphocytes	—

Countries

Japan

Contacts

Public ContactToshie Iijima

Dokkyo Medical University Department of Endocrinology and Metabolism

toshie@dokkyomed.ac.jp+81282861111

Outcome results