Patients with impaired fat absorption, or those with diarrhea, fatty stools, weight loss, anemia, etc., and suspected of having impaired fat absorption.
Conditions
Interventions
Patients will be given fat emulsified food 4 hours prior to the test day. Fat emulsified foods to be consumed are listed below. Lotte "
Sou"
190ml (Ingredients) Sugar (manufactured outside Japan, manufactured in Japan), vegetable oils and fats, dairy products, fructose, egg yolks (including eggs), foods made mainly from milk, dextrin, s
Sponsors
Fukuoka University Chikushi Hospital
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1) Patients with any kind of gastrointestinal disease that requires upper gastrointestinal endoscopy. 2) Patients over 20 years old. 3) Patients who are able to consume fat emulsified food. 4) Patients who have given written consent to participate in the study.
Exclusion criteria
Exclusion criteria: 1) Patients at high risk of bleeding during biopsy due to antithrombotic, anticoagulant, or antiplatelet medication. 2) Patients at high risk of bleeding from biopsy due to underlying diseases such as hepatic insufficiency, renal insufficiency, or blood coagulation abnormalities. 3) Patients with a history of gastrectomy. 4) Patients with lactose intolerance. 5) Other patients who are judged inappropriate for this study by the investigator or sub-investigator.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| To determine the endoscopic findings of the duodenal mucosa characteristic of gastrointestinal diseases with impaired fat absorption observed after fat emulsified food loading. | — |
Secondary
| Measure | Time frame |
|---|---|
| 1) To determine the morphological characteristics of WOS-positive and WOS-negative duodenal mucosa observed by NBI magnification endoscopy after fat emulsified food loading will be determined. 2) To determine the pathological characteristics of WOS-positive and WOS-negative duodenal mucosa observed by NBI magnifying endoscopy after fatty emulsified food loading. 3) To determine the pathological characteristics of WOS-positive and WOS-negative duodenal mucosa observed by NBI magnifying endoscopy after fatty emulsified food loading. 3. to determine the characteristics of endoscopic findings of gastric mucosa (non-white light magnification, non-NBI magnification, and magnification with NBI) observed after fat emulsified food loading. 4) Determine the characteristics of endoscopic findings (non-magnified white light, non-magnified NBI, magnified NBI) of esophageal Barrett's epithelium observed after fat emulsified food loading. 5) To determine the relationship between the characteristics of the above endoscopic findings and the clinicopathological characteristics of the target patients. | — |
Countries
Japan
Contacts
Public ContactTakao Kanemitsu
Fukuoka University Chikushi Hospital Department of Endoscopy
Outcome results
None listed