Studies of changes in cerebral blood flow and brain function using Near-infrared spectroscopy in laparoscopic hepatectomy.

Studies of changes in cerebral blood flow and brain function using Near-infrared spectroscopy in laparoscopic hepatectomy. - Studies of changes in cerebral blood flow and brain function using Near-infrared spectroscopy in laparoscopic hepatectomy.

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

JPRN

Registry ID

JPRN-UMIN000047087

Enrollment

Registered

2022-04-01

Start date

2022-04-01

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Hepatocellular carcinoma and Inguinal hernia

Interventions

None listed

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: (1) Patients with PS (ECOG classification) of 0 to 1 (2) Patients who retain the functions of major organs (bone marrow, liver, kidney, lungs, etc.) White blood cell count: 12000/mm3 or less Number of neutrophils: 1500/mm3 or more Amount of hemoglobin: 9.0 g/dl or more Platelet count: 100000/mm3 or more Total bilirubin: 2.0 mg/dl or less (patients undergoing jaundice reduction for obstructive jaundice should be 3.0 mg/dl or less). AST and ALT values: 150 U/L or less Creatinine: 1.5mg/dl or less Creatinine clearance is 50 mL/min or more (use the estimation formula of Cockcroft-Gault method. If there is an actual measurement value, give priority to the actual measurement value) Estimate formula = body weight (kg) * (140-age) / 72 * serum creatinine value (mg/dL). For women, multiply the value obtained by 0.85 (3) Patients who can take orally (4) Patients who have given written consent to be the subject of this study (5) Adults aged 18 years or older who have sufficient judgment to obtain consent for this study (6) Patients with or without suspicion of infectious disease

Exclusion criteria

Exclusion criteria: (1)Patients who are contraindicated for MRI and SPECT (2) Patients who are difficult to tolerate surgery (3) Patients with active infectious diseases (fever 38.0 celsius or higher) (4) Patients who may be pregnant or pregnancy (5) Underage patients (under 18 years old) (6) Patients who do not have sufficient judgment to obtain consent for the study (7) Patients with bilateral inguinal hernias, donor patients (8) Patients who are judged to be inappropriate for conducting this study safely by physician

Design outcomes

Primary

Measure	Time frame
Measurement of cerebral blood flow and changes in oxygen metabolism by Near-infrared spectroscopy	—

Secondary

Measure	Time frame
Intelligence test, brain MRI, brain SPECT	—

Countries

Japan

Contacts

Public ContactTomohiro Iwasa

Iwate Medical University department of surgery

itomo@iwate-med.ac.jp019-613-7111

Outcome results