Investigation of saliva IgG neutralizing antibodies after vaccination against SARS-CoV-2

Correlation between saliva IgG neutralizing antibodies and blood IgG neutralizing antibodies after vaccination against SARS-CoV-2 - Correlation between saliva IgG and blood IgG neutralizing antibodies after SARS-CoV-2 vaccination

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000047028

Enrollment

Registered

2022-03-01

Start date

2022-03-01

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

COVID-19

Interventions

Specimens will be collected before the third dose of vaccine against SARS-CoV-2 and 3 weeks after the third dose of vaccine.

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Subjects who are scheduled to receive three doses of vaccine

Exclusion criteria

Exclusion criteria: Subjects who have been infected with the SARS-CoV-2 infection

Design outcomes

Primary

Measure	Time frame
Determine whether neutralizing IgG antibodies increase in blood, but also correlate and increase in saliva. Correlation coefficients of 7 or higher will be used as outcome measures.	—

Countries

Japan

Contacts

Public ContactKeiichi Tsukinoki

Kanagawa Dental University School of Dentistry

tsukinoki@kdu.ac.jp+81468228866

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026