Healthy adults
Conditions
Interventions
Overfeeding condition (150% of energy requirement) Intervention periods was 8 days (4 days in free living conditions and 4 days in laboratory conditions).
Control condition (100% of energy requiremen
Sponsors
National Institutes of Biomedical Innovation, Health and Nutrition
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: Subjects will be adult males aged 20 years or older who have given informed consent for this study.
Exclusion criteria
Exclusion criteria: 1.Under 20 years old 2.BMI over 30 kg/m2 3.Patients with regular medication (diabetes treatment, alpha-blockers, beta-blockers, and other medications that affect metabolism) 4.Those who have diseases that affect metabolism (diabetes, thyroid disorders) 5.Those with a diagnosis of or history of mental illness 6.Patients with pacemakers or other implantable medical devices 7.Those with serious cardiovascular disease. 8.Those with acute stage cancer. 9.Those who have a history of gastrointestinal surgery (mainly esophagus, stomach, duodenum, small intestine, colon, and liver. However, appendicectomy is acceptable) 10.Those with knee or back problems that interfere with daily life. 11.Those who have extremely irregular eating habits. 12.Those who have exercise habits (average 60 minutes/day or more) 13.Those who are currently participating in, or intend to participate in, a study involving the ingestion of other foods, the taking of drugs, or the application of cosmetics or drugs, etc. 14.Those with drinking and smoking habits and cannot be controlled during the study period
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Energy loss from stool and urine. The intervention period will consist of three different energy balance conditions for eight days each. | — |
Secondary
| Measure | Time frame |
|---|---|
| Energy loss of nutrients (protein, carbohydrate, and fat), body weight, blood glucose variability, gut microbiota, and metabolites | — |
Countries
Japan
Contacts
Public ContactEIICHI Yoshimura
National Institutes of Biomedical Innovation, Health and Nutrition Center for Clinical Nutrition
Outcome results
None listed