Alzheimer'
Conditions
Interventions
PET with 18F-PMPBB3 / Neurops ychological tests
PET with 18F-PMPBB3 / Neurops ychological tests
PET with 18F-PMPBB3 / Neurops ychological tests
Sponsors
Institute for Quantum Medical Science, Quantum Life and Medical Science Directorate, National Institutes for Quantum Science and Technology (QST)
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: Patients diagnosed with MCI or AD The diagnostic criteria for each disease shall be as follows. 1) MCI: Patients who meet the diagnostic criteria of Petersen (2) AD: Patients who meet the diagnostic criteria of NINCDS-ADRDA Healthy volunteer group 1) Those who have the ability to give consent to participate in this study, and who can read and understand the consent explanatory document.
Exclusion criteria
Exclusion criteria: Patients diagnosed with MCI or AD 1) Patients with a history of or complications from organic brain disease (disorders of consciousness, head trauma requiring hospitalization, obvious cerebral infarction or cerebral hemorrhage, etc.) (2) Those who have substance-related disorders (e.g., drug dependence). (3) Those who have complications from serious diseases, or those who have a history of such complications and are judged by the physician as the researcher to be inappropriate for this research. (4) Those with pacemakers or internal metal devices (brain clips, bolts, etc.) (5) Those with tattoos (including tattoos and art makeup) (6) Those who are highly claustrophobic (7) Patients who are pregnant or may be pregnant, and those who are breastfeeding (8) Others who are judged inappropriate as research subjects by the researcher's physician. Healthy volunteer group 1) Subjects with a history of or complications from organic brain disease (disorders of consciousness, head trauma requiring hospitalization, obvious cerebral infarction or cerebral hemorrhage, etc.) (2) Those who have substance-related disorders (e.g., drug dependence). (3) Those who have complications from serious diseases, or those who have a history of such complications and are judged by the physician as the researcher to be inappropriate for this research. (4) Those with pacemakers or internal metal devices (brain clips, bolts, etc.) (5) Those with tattoos (including tattoos and art makeup) (6) Those who are highly claustrophobic (7) Patients who are pregnant or may be pregnant, and those who are breastfeeding (8) Subjects who are judged inappropriate as research subjects by the researcher's physician.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Quantitative evaluation of the distribution of [11C]K-2 | — |
Countries
Japan
Contacts
Public ContactKeisuke Takahata
Institute for Quantum Medical Science, Quantum Life and Medical Science Directorate, QST Department of Functional Brain Imaging
Outcome results
None listed