Preventive effect of salt intake at blood donation site on vasovagal reaction.

A quasi-randomized controlled trial on prevention of delayed vasovagal reaction by salt intake at blood donation site. - A quasi-randomized controlled trial on prevention of delayed vasovagal reaction by salt intake at blood donation site.

Status

Recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000046902

Enrollment

458252

Registered

2022-03-01

Start date

2022-03-15

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Vasovagal reaction

Interventions

Eat 3 candies containing salt (0.108g of salt per 1 candy) prior to blood donation. Donate blood according to usual protocol.

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Eligibility criteria: 1) person who is willing to donate blood and visiting blood donation site, and eligible for blood donation. 2) person who is willing to donate 400mL whole blood.

Exclusion criteria

Exclusion criteria: Exclusion criteria: Blood donors are excluded from this trial if 1) they are under salt restriction by their doctors, or 2) they are allergic for dairy products, or 3) their informed consent may not be obtained,

Design outcomes

Primary

Measure	Time frame
Incidence of VVR in 3 different phase of blood donation. ( i.e. before needle removal, within 20 minutes after needle removal, and more than 20 minutes after needle removal.).	—

Secondary

Measure	Time frame
Comparison of incidence of VVR after adjustment by age, sex, estimated blood volume, and donation history.	—

Countries

Japan

Contacts

Public ContactNoriko Namba

Japanese Red Cross Tokyo Metropolitan Blood Center Division of medical affairs

n-namba@ktks.bbc.jrc.or.jp0352723532

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026