A study on oral care and saliva IgA

A study on professional oral care and saliva IgA concentration - Professional oral care and saliva IgA concentration

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000046865

Enrollment

Registered

2022-02-10

Start date

2022-02-10

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Oral disease

Interventions

In addition to the full mouth disinfection concept proposed by Quirynen of Catholic University, a medium to long chain split polyphosphoric acid solution is applied instead of chlorhexidine used in Qu

s method. While suppressing odontogenic bacteremia, normal scaling is performed on the entire jaw in a short period of time to remove plaque and tartar, including biofilm, from the tooth surface, peri

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Patients with periodontal disease who have had an intraoral examination (conventional periodontal examination: X-ray, PCR, probing, etc.).

Exclusion criteria

Exclusion criteria: Patients with intestinal diseases.

Design outcomes

Primary

Measure	Time frame
By inhibiting the influx of oral bacteria into the intestinal tract through oral care, the index will be whether salivary IgA increases after 2 weeks compared to before the intervention.	—

Countries

Japan

Contacts

Public ContactKeiichi Tsukinoki

Kanagawa Dental University School of Dentistry

tsukinoki@kdu.ac.jp0468228866

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026