MicroRNA Markers in Bile for the Diagnosis of Pancreatic and Biliary-Tract Cancers

MicroRNA Markers in Bile for the Diagnosis of Pancreatic and Biliary-Tract Cancers - MicroRNA Markers in Bile for the Diagnosis of Pancreatic and Biliary-Tract Cancers

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

JPRN

Registry ID

JPRN-UMIN000046730

Enrollment

120

Registered

2022-01-26

Start date

2019-04-01

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

pancreatic cancer and biliary tract cancer

Interventions

None listed

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: The study population consisting of patients with PC, BTC, benign biliary obstruction who underwent ERCP or PTBD for the purpose of biliary drainage, and pathologically confirmed of bile at the Department of Gastroenterology and Hepatology, Nihon University School of Medicine between April 2019 and May 2023. From this population, we selected patients having available surplus storage bile and serum.All patients signed an informed consent form for research prior to biliary drainage or blood sampling being performed.

Exclusion criteria

Exclusion criteria: Patients with prior chemotherapy due to PC and BTC or cancers of other organs were excluded from the study.

Design outcomes

Primary

Measure	Time frame
to assess the utility of select miRNAs as diagnostic markers for differentiating PC from BTC and from individuals without PC and BTC by comparing the differential expression of miRNAs in bile among individuals with PC, BTC and benign biliary obstruction.	—

Countries

Japan

Contacts

Public ContactNoriyuki Kuniyoshi

Nihon University Itabashi Hospital Division of Gastroenterology and Hepatology

kuniyoshi.noriyuki@nihon-u.ac.jp03-3972-8111

Outcome results