A multicenter retrospective study of the efficacy of statins in unresectable or recurrent advanced biliary tract cancer patients.

A multicenter retrospective study of the efficacy of statins in unresectable or recurrent advanced biliary tract cancer patients. - A multicenter retrospective study of the efficacy of statins in unresectable or recurrent advanced biliary tract cancer patients.

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

JPRN

Registry ID

JPRN-UMIN000046659

Enrollment

1500

Registered

2022-01-17

Start date

2021-12-01

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Biliary tract cancer

Interventions

None listed

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1) Patients diagnosed with unresectable advanced recurrent biliary tract cancer between January 1, 2016 and March 31, 2021. 2) Patients who have received palliative chemotherapy for unresectable advanced recurrent biliary tract cancer. Or, patients who are under the Best Supportive Care (BSC) policy for unresectable advanced recurrent biliary tract cancer and have not received palliative chemotherapy for other carcinomas since diagnosis. 3) Patients with a histological diagnosis of adenocarcinoma or adenosquamous carcinoma, or patients with cytological detection of Adenocarcinoma Class V if the diagnosis is difficult to make by histology.

Exclusion criteria

Exclusion criteria: None

Design outcomes

Primary

Measure	Time frame
Overall survival of 1st line paliative chemotherapy (including best supportive care).	—

Secondary

Measure	Time frame
Overall survival by treatment type in first-line treatment, progression-free survival by treatment type in first-line treatment, and the relationship between survival and the presence of Actionable gene mutations suggested to be associated with statins by cancer genome panel testing.	—

Countries

Japan

Contacts

Public ContactKai Tsugaru

Keio University Hospital Department of Internal Medicine, Division of Gastroenterology and Hepatology

kait721@keio.jp+81333531211

Outcome results