Follow-Up study of paTients UndeRgoing cathEter ablation for Atrial Fibrillation: evaluation of long-term outcomes and predictive factors based on genetic predisposition

Follow-Up study of paTients UndeRgoing cathEter ablation for Atrial Fibrillation: evaluation of long-term outcomes and predictive factors based on genetic predisposition - FUTURE-AF Study

Status

Recruiting

Phases

Unknown

Study type

Observational

Source

JPRN

Registry ID

JPRN-UMIN000046658

Enrollment

5000

Registered

2022-01-17

Start date

2021-09-01

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

atrial fibrillation

Interventions

None listed

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: (1) Patients who undergo radiofrequency catheter ablation for atrial fibrillation during the period from the approval of the ethical review of clinical research to December 31, 2026. (2) Age 20 years or older

Exclusion criteria

Exclusion criteria: Patients who are judged by the attending physician to be unsuitable for participation in the study

Design outcomes

Primary

Measure	Time frame
Association between genetic markers or genetic risk scores and cardiovascular events at 36 months post catheter ablation	—

Secondary

Measure	Time frame
Association between genetic markers or genetic risk scores and atrial fibrillation recurrence at 36 months post catheter ablation Association between genetic markers or genetic risk scores and implantation of cardiac devices at 36 months post catheter ablation Association between genetic markers or genetic risk scores and clinical backgrounds Association between genetic markers or genetic risk scores and echocardiographic data Association between genetic markers or genetic risk scores and electrocardiographic findings Association between genetic markers or genetic risk scores and electrophysiological findings Association of genetic markers, genetic risk scores with clinical scores such as CHADS2 score, CHA2DS2-Vasc score, HASBLED score and comparison of the performance between the scores Genome-wide association analysis using study participants as atrial fibrillation cases Association of blood biomarkers with genetic markers and genetic risk scores Association between blood biomarkers and atrial tachyarrhythmia recurrence rate at 36 months post catheter ablation Association between blood biomarkers and cardiovascular events at 36 months post catheter ablation	—

Measure

Time frame

Association between genetic markers or genetic risk scores and atrial fibrillation recurrence at 36 months post catheter ablation Association between genetic markers or genetic risk scores and implantation of cardiac devices at 36 months post catheter ablation Association between genetic markers or genetic risk scores and clinical backgrounds Association between genetic markers or genetic risk scores and echocardiographic data Association between genetic markers or genetic risk scores and electrocardiographic findings Association between genetic markers or genetic risk scores and electrophysiological findings Association of genetic markers, genetic risk scores with clinical scores such as CHADS2 score, CHA2DS2-Vasc score, HASBLED score and comparison of the performance between the scores Genome-wide association analysis using study participants as atrial fibrillation cases Association of blood biomarkers with genetic markers and genetic risk scores Association between blood biomarkers and atrial tachyarrhythmia recurrence rate at 36 months post catheter ablation Association between blood biomarkers and cardiovascular events at 36 months post catheter ablation

—

Countries

Japan

Contacts

Public ContactTAKANORI YAMAGUCHI

Saga University Hospital Department of Cardiovascular Medicine

takanori@cc.saga-u.ac.jp0952342443

Outcome results