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Changes of resting-state brain function after acceptance and commitment therapy for persistent postural-perceptual dizziness

Changes of resting-state brain function after acceptance and commitment therapy for persistent postural-perceptual dizziness - Changes of brain function after ACT for PPPD

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
JPRN
Registry ID
JPRN-UMIN000046606
Enrollment
30
Registered
2022-01-17
Start date
2022-01-19
Completion date
Unknown
Last updated
2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

persistent postural-perceptual dizziness

Interventions

Acceptance and commitment therapy combined with vestibular rehabilitation (6 weekly group therapy sessions of 120 minutes each)

Sponsors

Nagoya City Unversity
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: 1) Visiting a neuro-otologist with a chief complaint of dizziness, unsteadiness, or non-spinning vertigo. 2) Meets the diagnostic criteria for persistent postural-perceptual dizziness. 3) Total score of 16 or more on the Dizziness Handicap Inventory. 4) From 20 years old to 64 years old. 5) Written consent.

Exclusion criteria

Exclusion criteria: 1) Physical conditions that make it difficult to conduct psychotherapy or vestibular rehabilitation. 2) Psychiatric disorders other than DSM-5 anxiety disorders, somatic symptom disorder, or illness anxiety disorder diagnosed by a psychiatrist. 3) A history of DSM-5 schizophrenia or bipolar disorder diagnosed by a psychiatrist. 4) Suicidal ideation or self-injury determined by a psychiatrist. 5) SSRI or SNRI initiation or dose increase in the last month. 6) Receiving another cognitive behavioral therapy during the study period. 7) Receiving any otolaryngological treatment other than pharmacotherapy for vestibular diseases during the study period. 8) Difficulty in coming to our clinic during the study period. 9) Pregnant or planning to become pregnant. 10) Inadequate understanding of Japanese language. 11) Family members living with the researchers. 12) Contraindicated or unsuitable for MRI. 13) Abnormalities that are not suitable for analysis of MRI.

Design outcomes

Primary

MeasureTime frame
MRI image Handicap due to dizziness (Dizziness Handicap Inventory) Frequency of vestibular symptoms (Vertigo Symptom Scale-short form)

Secondary

MeasureTime frame
Anxiety and Depressive symptoms (Hospital Anxiety and Depression Scale) Insomnia (Insomnia Severity Index) QOL (EuroQol-5 Dimensions-5 Level) Burden by somatic symptoms (Somatic Symptom Scale-8) Exacerbation factors of PPPD (Niigata PPPD Questionnaire) Health anxiety (Short Health Anxiety Inventory) Alexithymia (Tronto Alexithymia Scale-20) Mindfulness (Mindfulness Attention Awareness Scale) Interoceptive awareness (Multidimensional Assessment of Interoceptive Awareness) Recovery process (Recovery Assessment Scale) Psychological flexibility (Acceptance and Action Questionnaire-2) Valued action (Valuing Questionnaire) Cognitive fusion (Cognitive Fusion Questionnaire) Patient's global Impression of Change

Countries

Japan

Contacts

Public ContactMasaki Kondo

Nagoya City University Graduate School of Medical Sciences Department of psychiatry and Cognitive-Behavioral Medicine

kondo-masaki@umin.ac.jp052-853-8271

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026