Effects of Anesthetics on Perioperative Oxygen Supply and Demand Balance: A Comparison of Propofol and Remimazolam

Effects of Anesthetics on Perioperative Oxygen Supply and Demand Balance: A Comparison of Propofol and Remimazolam - Effects of Anesthetics on Perioperative Oxygen Supply and Demand Balance: A Comparison of Propofol and Remimazolam

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000046531

Enrollment

Registered

2022-01-05

Start date

2022-01-04

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Laparotomy under general anesthesia

Interventions

Remimazolam group Propofol group

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Surgical cases undergoing general anesthesia in our operating room are eligible. Eligible surgical procedures are laparotomies with a scheduled duration of at least 2 hours and no more than 6 hours.

Exclusion criteria

Exclusion criteria: Allergy to remimazolam or propofol, history of central disease, history of neurobacterial disease, uncontrolled cardiac or respiratory failure, renal or hepatic insufficiency, inability to consent to research, procedures requiring isolated lung ventilation, emergency surgery.

Design outcomes

Primary

Measure	Time frame
Rate of change of oxygen consumption and carbon dioxide production in the perioperative period	—

Countries

Japan

Contacts

Public Contactkenya yarimizu

Yamagata University Medical School Hospital Department of Anesthesiology

yarimizu.kenya@gmail.com0236331122

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026