Development and evaluation of a nursing program for promoting self-regulation of lung cancer patients to prevent deterioration of dermatologic toxicity associated with epidermal growth factor receptor-tyrosine kinase inhibitor treatment

Development and evaluation of a nursing program for promoting self-regulation of lung cancer patients to prevent deterioration of dermatologic toxicity associated with epidermal growth factor receptor-tyrosine kinase inhibitor treatment - Development and evaluation of a nursing program for promoting self-regulation of lung cancer patients to prevent deterioration of dermatologic toxicity associated with EGFR-TKI treatment

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000046506

Enrollment

Registered

2022-01-10

Start date

2022-01-05

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Lung cancer

Interventions

Providing knowledge about skin care using materials and practicing skin care methods. During the 12 to 16 weekly survey period, the patient observes the skin condition, measures the keratin water cont

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1) It is judged by the medical staff that the physical and mental condition is stable and there is no deterioration of cognitive function. 2) Over 20 years old 3) The attending physician and the nurse in charge judge that it is possible to participate in the research. 4) Communication in Japanese is possible 5) Understand the purpose of this research and obtain consent to participate.

Exclusion criteria

Exclusion criteria: 1) Physical and psychological distress is significant and participation in a nursing program becomes a burden 2) Things that cannot be communicated in Japanese 3) Cognitive function is impaired and self-management of drugs and skin care is difficult 4) Those who do not agree to participate in the research

Design outcomes

Primary

Measure	Time frame
The survey period is pre-intervention / at the start of the survey (T0), immediately after the end of the intervention / 8-12 weeks after the first survey (T1), 1 month after the end of the intervention / 1 month after the end of the second survey (T2). The primary outcomes are Dermatology Life Quality Index, severity of skin disorders, keratin water content, and no interruption or discontinuation of EGFR-TKI.	—

Measure

Time frame

The survey period is pre-intervention / at the start of the survey (T0), immediately after the end of the intervention / 8-12 weeks after the first survey (T1), 1 month after the end of the intervention / 1 month after the end of the second survey (T2). The primary outcomes are Dermatology Life Quality Index, severity of skin disorders, keratin water content, and no interruption or discontinuation of EGFR-TKI.

—

Secondary

Measure	Time frame
The survey period is pre-intervention / at the start of the survey (T0), immediately after the end of the intervention / 8-12 weeks after the first survey (T1), 1 month after the end of the intervention / 1 month after the end of the second survey (T2). The secondary outcomes are self-efficacy scale for cancer patients, skin observation and skin care implementation.	—

Countries

Japan

Contacts

Public ContactYoshie Tokuoka

Osaka Metropolitan University School of Nursing

tokuokay@omu.ac.jp0729502111

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026