Healthy adults
Conditions
Interventions
Intake of active food once a day for 8 weeks.
Intake of placebo food once a day for 8 weeks.
Sponsors
Kao Corporation
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1)Males and females aged 20 to 59 years old at the time of informed consent. 2)Those who have subjective symptoms of dry, red and itchy skin. 3)Those who have any of the followings. a. past diagnosis of allergic diseases. b. subjective allergy-related symptoms. c. family members with allergy diseases. 4)Those whose BMI is in the normal range (18.5 to 30.0). 5)Those who are judged appropriate by the study director or person in charge.
Exclusion criteria
Exclusion criteria: 1) Those who currently attend a clinic for treatment of skin diseases. 2) Those who currently attend a clinic for treatment of allergic diseases. 3) Those who attend a clinic for treatment of seasonal rhinitis every year. 4) Those who have experienced allergic symptoms due to the intake of certain foods. 5) Those who attend or attended a clinic within a month before the trial for treatment of the diseases which are considered to influence the outcome. 6) Those who have been infected with viruses of hepatitis B or C, syphilis or HIV. 7) Those who use drugs which are considered to influence the outcome within two weeks before the trial. 8) Those who regularly take certain supplements or have plan to take them during the trial period. 9) Those who have excessive sunburn on the test sites. 10) Those who have experienced cosmetic operation on the test sites. 11) Those who are strongly resistant to blood collection or have experienced sickness due to it. 12) Those who plan to participate in the other clinical trial during the trial period. 13) Heavy drinkers. 14) Smokers 15) Those who are currently pregnant or breastfeeding, or wish to become pregnant during the trial period. 16) Those who have the fever or respiratory symptoms in themselves or their family living together, or have close contact with the persons infected with COVID-19 within two weeks before the trial. 17) Those who are judged not appropriate by the study director or person in charge.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Transepidermal water loss Stratum corneum hydration Skin image analysis Allergy-related blood biomarkers | — |
Secondary
| Measure | Time frame |
|---|---|
| Japanese version of Skindex-16 Japanese Allergic Rhinitis Standard Quality of Life Questionnaire Other endpoints for exploratory analysis | — |
Countries
Japan
Contacts
Public ContactSatoko Fukagawa
Kao Corporation Biological Science Research
Outcome results
None listed