autoimmune retinopathy
Conditions
Interventions
None listed
Sponsors
Kobe University Graduate School of Medicine
Yamaguchi University Osaka University Yamagata University
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: [Patinet with autoimmune retinopathy] Patinet who meets all of the following: (1) sudden-onset visual disorder (2) no cause of visual disorder is specified in a routine clinical examination (3) abnotmal electroretinogram (4) absence of fundus findings and retnal degeneration/retinal distrophy which can explain visual disorder (5) absence of apparent ocular inflamation (6) presence of outer retinal abnormality on optical coherence tomography (OCT) [Healthy volunteer] Healthy adult who shows no ocular abnormality except for mild cataract
Exclusion criteria
Exclusion criteria: [Patinet with autoimmune retinopathy] (1) uveitis with specific cause (2) inherited retinal diseases (3) optic nerve disorders (4) opacification in anterior segment of the eye and/or optic media which precludes fundus assessment (5) drug-induced retinal disorders (6) aged younger than 20 years (7) patinet who disagrees with this study (8) patinet who the attending doctor judges as ineligibile to participate in this study [Healthy volunteer] Individual who disagrees with this study
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| change in best-corrected visual acuity improvement from baseline to 6 months | — |
Secondary
| Measure | Time frame |
|---|---|
| the following parameters during 6-month follow-up: (1) change in visual field from baseline to 6 months (2) change in optical coherence tomography findings (3) change in comprehenisive protein array data from blood samples (4) change in metabolome profile from blood samples (5) difference in comprehenisive protein array data from blood samples between patinets with autoimmune retinopathy and healthy volunteers (6) difference in metabolome profile from blood samples between patinets with autoimmune retinopathy and healthy volunteers (7) adverse events | — |
Countries
Japan
Contacts
Public ContactSentaro Kusuhara
Kobe University Graduate School of Medicine Division of Ophthalmology, Department of Surgery
Outcome results
None listed