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Examination of predictors of development into truancy and withdrawal by salivary stress biomarkers in children with developmental disorders

Examination of predictors of development into truancy and withdrawal by salivary stress biomarkers in children with developmental disorders - Examination of predictors of development into truancy and withdrawal by salivary stress biomarkers in children with developmental disorders

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
JPRN
Registry ID
JPRN-UMIN000046413
Enrollment
200
Registered
2021-12-20
Start date
2020-07-08
Completion date
Unknown
Last updated
2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Autism spectrum disorder

Interventions

Questionnaire head MRI saliva collection

Sponsors

Nara Medical University
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: (1) ASD group Patients diagnosed by the Diagnostic and Statistical Manual of Mental Disorders, Fifth Edition (DSM-5) and ADOS2. (2) ADHD group Patients diagnosed by the Diagnostic and Statistical Manual of Mental Disorders, 5th edition (DSM-5). (3) Control group (HC) Healthy control subjects whose age and gender match those of the ASD and ADHD groups (assessed by the non-patient version of the Structured Interview for DSM-IV (SCID)). Translated with www.DeepL.com/Translator (free version)

Exclusion criteria

Exclusion criteria: (1) Patients with a history of head trauma with impaired consciousness, chronic lung disease, renal disease, chronic liver disease, thyroid disease, active cancer, cerebrovascular disease, epilepsy, neurological disease, or substance-related disorders (2) Patients with autoimmune diseases (SLE, hyperthyroidism: Graves' disease, ulcerative colitis, Crohn's disease, etc.) (3) Those with a verbal comprehension index of <70 on the Wechsler Intelligence Scale for Children (WISC) or the Wechsler Adult Intelligence Scale (WAIS) (4) Patients with a clear history of psychotic symptoms (5) Patients who regularly use steroids and NSAIDs Translated with www.DeepL.com/Translator (free version)

Design outcomes

Primary

MeasureTime frame
Strong factors as causes of truancy

Countries

Japan

Contacts

Public Contactkazuhiko Yamamuro

Nara Medical University Psychiatry

muro@naramed-u.ac.jp0744-22-3051

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026