Impact of Multiple Ballooning on Coronary Plaque as Assessed by Intravascular Ultrasound and Optical Coherence Tomography

Impact of Multiple Ballooning on Coronary Plaque as Assessed by Intravascular Ultrasound and Optical Coherence Tomography - REACT

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

JPRN

Registry ID

JPRN-UMIN000046395

Enrollment

Registered

2021-12-16

Start date

2021-11-10

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Chronic coronary syndrome

Interventions

None listed

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: patients with chronic coronary syndrome undergoing PCI

Exclusion criteria

Exclusion criteria: 1. Acute coronary syndrome. 2. Acute decompensated heart failure. 3. Non-dialysis patients with chronic kidney disease (CKD Stage 4-5: eGFR <30 ml/min/1.73m2). 4. Severe coronary artery calcification undergoing PCI using debulking device. 5. Ostial lesions of left main or right coronary arteries. 6. Contraindication or hypersensitivity to anti-platelet agents or contrast media. 7. Female of childbearing potential or breastfeeding. 8. Patients who are considered inappropriate for the study by the operator.

Design outcomes

Primary

Measure	Time frame
Difference in mean lumen area from baseline to post-balloon as assessed by OCT	—

Secondary

Measure	Time frame
Difference in the following variables from baseline to post-balloon as assessed by OCT Minimal lumen area Eccentricity index Mean dissection angle Maximum dissection angle Mean dissection length Difference in the following variables from baseline to post-balloon as assessed by IVUS Minimal lumen area Mean Lumen area Minimal Vessel area Mean Vessel area Mean Plaque area Lumen volume Plaque volume Vessel volume Lumen volume Index Plaque volume Index Vessel volume Index Percent atheroma volume Sub-group analysis Elderly Gender Hemodialysis Diabetes Small vessel Plaque type Plaque angle	—

Measure

Time frame

Difference in the following variables from baseline to post-balloon as assessed by OCT Minimal lumen area Eccentricity index Mean dissection angle Maximum dissection angle Mean dissection length Difference in the following variables from baseline to post-balloon as assessed by IVUS Minimal lumen area Mean Lumen area Minimal Vessel area Mean Vessel area Mean Plaque area Lumen volume Plaque volume Vessel volume Lumen volume Index Plaque volume Index Vessel volume Index Percent atheroma volume Sub-group analysis Elderly Gender Hemodialysis Diabetes Small vessel Plaque type Plaque angle

—

Countries

Japan

Contacts

Public ContactYusuke kanzaki

Shinshu University School of Medicine Department of Cardiovascular Medicine

kanzaki@shinshu-u.ac.jp0263-37-3486

Outcome results