A multicenter prospective study to evaluate the utility of animal naming test for the diagnosis of covert hepatic encephalopathy

A multicenter prospective study to evaluate the utility of animal naming test for the diagnosis of covert hepatic encephalopathy - A multicenter prospective study to evaluate the utility of animal naming test for the diagnosis of covert hepatic encephalopathy

Status

Recruiting

Phases

Unknown

Study type

Observational

Source

JPRN

Registry ID

JPRN-UMIN000046313

Enrollment

500

Registered

2021-12-08

Start date

2021-12-08

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Liver cirrhosis

Interventions

None listed

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1. Patients with cirrhosis or healthy volunteers aged 20 years or more 2. Written informed consent

Exclusion criteria

Exclusion criteria: 1.Patients with previous shunt operation or transjunglar intrahepatic portosystemic shunt 2.Patients with infection 3.Patients with overt hepatic encephalopathy, gastrointestinal bleeding, and spontaneous bacterial peritonitis within 4 weeks 4.Patient with alcohol abuse (60 g/day or more) within 4 weeks 5.Patients with neuromuscular disease which affect the results of the neuropsychological test 6.Patients who receive medications for dementia 7.Patients with severe comorbidities such as heart, renal, and respiratory failure 8.Patients who are inadequate for the study 9.Volunteers who are initially related to the study

Design outcomes

Primary

Measure	Time frame
The relationship between animal naming test and covert hepatic encephalopathy	—

Secondary

Measure	Time frame
The relationship between animal naming test and each variable (sarcopenia, frailty, falls, fracture, traffic accident, quality of life). The relationship between animal naming test and clinical outcomes (overt hepatic encephalopathy and mortality).	—

Countries

Japan

Contacts

Public ContactTakao Miwa

Gifu University Hospital The First Department of Internal Medicine

miwa_t@gifu-u.ac.jp058-230-6308

Outcome results