Adult
Conditions
Interventions
functional food Intake : 2,550 mg Ingesion : 56 day
Sponsors
Yamada Bee Company, Inc.
Research Center for Immunological Analysis, Inc.
Eligibility
Sex/Gender
Female
Inclusion criteria
Inclusion criteria: 1. Healthy Japanese men and women aged more than 40 years, less than 80 years at the time of giving informed consent. 2. Individuals who are aware of frequent urination, who are suffering from frequent urination. 3. Individuals who urinate more than once at night 4. Individuals who has freely given consent and has understood the purpose of the study. 5. BMI:18.5 - 30.0 6. Individuals who are considered fit for the enrollment in the clinical study.
Exclusion criteria
Exclusion criteria: 1. Individuals who undergoing treatment for urinary disorders such as overactive bladder, bladder inflammation, and urethral stones. 2. Individuals with a current history of diabetes, cerebrovascular accidents, sequelae of stroke, spinal cord disorders, spinal degenerative disorders, sleep disorders, and hypertension. 3. Individuals who have a disorder to absorption, distribution, metabolism, excretion of food, such as digestive tract, liver, kidney, heart and cardiovascular system. 4. Individuals with a history of the surgery considerable in the gastrointestinal tract site, for example, gastrectomy, stomach and intestines suturation, intestinal tract resection and so on. (Excluding polypectomy and appendectomy) 5. Individuals with current or history of uterine fibroids, endometriosis, or pelvic organ prolapse. 6. Individuals with a history of uterine or pelvic surgery. 7. Individuals who are receiving hormone replacement therapy (estrogen, progesterone preparations (drinks, patches, ointments), etc.), those who plan to take it during the study period. 8. Individuals who regularly overdose beverages containing diuretic ingredients. 9. Individuals with a history of allergies. 10. Individuals who regularly take health foods, supplements, and medicines that may affect the test. 11. Be Suspected alcohol or drug dependence. 12. Individuals who have smoked since 3 months of consent. 13. Individuals who participated in other clinical trial at resent (past 84 days) 14. Individuals with irregular lifestyles due to night shifts or shift work. 15. Individuals who live with or will participate in this test. 16. Individuals who cannot comply with the management items during this test. 17. Individuals who work for health food companies, cosmetics companies, pharmaceutical companies. 18. Individuals who judged by the investigator to be inappropriate for participating in the study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| frequency of nocturnal urination | — |
Secondary
| Measure | Time frame |
|---|---|
| Badder diary Questionnaire for urination and sleeping | — |
Countries
Japan
Contacts
Public ContactChizuru Fujikura
Yamada Bee Company, Inc. Functional research section, Institute for Bee Products & Health Science, R&D department
Outcome results
None listed