Healthy adult
Conditions
Interventions
Sponsors
EP Mediate Co., Ltd.
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: (1) Men and women between the ages of 20 and 64. (2) Subjects who are aware of itching due to dry skin. (3) Subjects who are judged by a doctor that treatment for atopic dermatitis is not necessary. (4) Subjects who fall under any one or more of the following atopic predispositions A: Relatives or subjects fall under any of the following ?Relatives (within 3rd degree) have a history of or are currently suffering from bronchial asthma, allergic rhinitis, conjunctivitis, atopic dermatitis, or more. ?Subject has a history of bronchial asthma, allergic rhinitis, conjunctivitis, atopic dermatitis, or more than one, and is not currently receiving treatment. B: Easy to produce IgE antibody
Exclusion criteria
Exclusion criteria: (1) Subjects who regularly use foods rich in lactic acid bacteria, health foods, and medicines at least three times a week. (2) Subjects who routinely take health foods that may affect the test results. (3) Subjects with experience in aesthetic medicine that affect the measurement site. (4) Subjects who received aesthetic medicine or hormone replacement therapy other than the measurement site from one year ago. (5) Subjects who have undergone esthetic treatment, scrubbing, or hair loss on the skin at the measurement site from one month ago to the end of the study. (6) Subjects who plan to get a sunburn due to long hours of outdoor work, etc. from one month ago to the end of the study. (7) Subjects who have a habit of washing their bodies by giving a strong stimulus to the measurement site. (8) Subjects who regularly use bath salts or subjects who have a habit of taking a hot spring at a frequency of 1 day or more a month. (9) Subjects with skin disorders at the measurement site. (10) Subjects who feel that rough skin occurs at the measurement site before and after menstruation. (11) Night and day shift worker. (12) Subjects who plan to travel abroad during the research period. (13) Subjects who have serious diseases, or diseases that affect the secretion of sex hormones, or have a history thereof. (14) Subjects who may develop allergic-like symptoms with research foods. (15) Subjects with a disease under treatment that affects the evaluation of this study, or with a history of serious illness. (16) Subjects whose pre-examination test values are significantly out of the reference range. (17) Subjects who have participated in other clinical studies within one month or will participate in. (18) Subjects who are planned to become pregnant or are pregnant or lactating. (19) Subjects who are judged as unsuitable for the study based on the results of lifestyle questionnaire. (20) Subjects judged as unsuitable for the study by the investigator.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Skin measurement (stratum corneum water content, transepidermal water loss, color difference (a *, L *)) QOL questionnaire (SKINDEX16, DLQI, SF-36, VAS questionnaire) Evaluate before, 4 weeks and 8 weeks after intake. | — |
Secondary
| Measure | Time frame |
|---|---|
| Inflammation-related markers Evaluate before, 4 weeks and 8 weeks after intake. | — |
Countries
Japan
Contacts
Public ContactKeiji Yamamoto
EP Mediate Co., Ltd. Foods Department, Trial Planning Section
Outcome results
None listed