mild cognitive impairment, mild dementia
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1) The patients with persistent cognitive decline detected by themselves or family members. 2) The patients diagnosed by neurologist as mild cognitive impairment (MCI) or dementia in the early stage. 3) the dose and usage of dementia medications are stable for at least 12 weeks before the participation 4) the mother language is Japanese
Exclusion criteria
Exclusion criteria: 1) the patients with a moderate or severe psychiatric disease such as depression 2) the patients with difficulty in psychological test or "kanji" training, for example with visual or hearing impairment or language disorders. 3) the patients with difficulty in the participation by comorbid medical diseases. 4) The patients with a brain organic lesions or significant abnormal findings in the blood tests.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| MMSE-J score(before, immediately after and 6-months after the cognitive training) | — |
Secondary
| Measure | Time frame |
|---|---|
| 1. ADAS (Alzheimer's Disease Assessment Scale) score 2. the score of Logical Memory Test from WMS-R (Wecheler Memory Scale Revised) 3. the score of Block Design from WAIS-IV (Wechsler Adult Intelligence Scale-4th edition) 4. TMT-J (Trail Making Test-Japanese) score 5. WF (verbal fluency test) score 6. JART (Japanese Adult Reading Test) score 7. DEMQOL, the assessment health-related quality of life, score 8. the achievement rate and accuracy of "kanji" training 9. the Questionnaire about the habit of "kanji" training 10. the questionnaire about writing habit 11. the score of 20 questions of "kanji" | — |
Countries
Japan
Contacts
Kyoto University Hospital Department of Neurology