Bronchial asthma
Conditions
Interventions
single-inhaler triple therapy for 12 weeks
Sponsors
Department of Respiratory Medicine, Tohoku Rosai Hospital
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1) Patients of both sexes aged 20 years and older 2) Patients with a diagnosis of asthma or cough variant asthma who have been receiving ICS or ICS/LABA for at least four weeks before they participate in the study, and with an ACQ-6 score of at least 1.5 at the screening 3) Patients who signed informed consent form before enrolling the study
Exclusion criteria
Exclusion criteria: 1) Patients with malignant tumor 2) Patients with COPD or patients with a smoking history of 10 pack-years or more 3) Patients with a smoking history in last 6 months 4) Patients with benign prostatic hypertrophy or glaucoma 5) Any patients considered to be inappropriate for this study by the principal investigator based on their background, physical examination, etc.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The comparison of clinical characteristics between the group of uncontrolled asthma improved at least 0.5 point from the baseline ACQ-7 by single-inhaler triple therapy and the group without effect (baseline %FE1, FeNO, exacerbation frequency, peripheral blood eosinophil count, and so on) | — |
Secondary
| Measure | Time frame |
|---|---|
| 1)Proportion of patients with at least 0.5 decrease in ACQ-7 score 2)Adverse event | — |
Countries
Japan
Contacts
Public ContactToshiyasu Yatsu
Tohoku Rosai Hospital Department of Respiratory Medicine
Outcome results
None listed