Acute heart failure
Conditions
Interventions
severe low-sodium diet group (salt restriction 3g/day)
normal low-sodium diet group (6g/day)
Sponsors
Juntendo University
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1) Age 20 years or older at the time of obtaining consent 2) Patients hospitalized for worsening heart failure with symptoms of heart failure (e.g., respiratory distress at rest or with light exertion) and signs of congestion (e.g., edema, moist chest rales, congestive chest radiographs) (left ventricular ejection fraction is not required) 3) NYHA classification II-IV 4) NT-proBNP becomes more than 1200 pg/mL or BNP becomes more than 300 pg/mL at the time of admission 5) Patients whose condition has been stabilized by initial treatment and are judged to be able to take oral intake
Exclusion criteria
Exclusion criteria: 1) Patient refuses to participate 2) Patients who are judged by their physician to be unable to start a full meal 3) Pregnancy 4) Others who are judged by the principal investigator to be inappropriate as research subjects
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Percent change in NT-proBNP from the day of the meal to 1 week later | — |
Countries
Japan
Contacts
Public ContactTaishi Dotare
Juntendo University Graduate School of Medicine Department of Cardiovascular Biology and Medicine
Outcome results
None listed