Skip to content

Brain imaging of dementia

Molecular imaging for pathophysiologic evaluation of dementia-related neurodegenerative diseases - Molecular imaging of dementia

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
JPRN
Registry ID
JPRN-UMIN000046094
Enrollment
150
Registered
2021-11-17
Start date
2023-03-31
Completion date
Unknown
Last updated
2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Patients with dementia and healthy subjects of the same age group who meet all the criteria.

Interventions

This is an observational study, but imaging results will open to patients. Controls continue self-followup. Imaging results may be opened to subjects if they are positive.

Sponsors

University of Fukui
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: Patients with MCI or early-stage dementia whose written consent has been freely given by the patient, and healthy people who participate of their own free will.

Exclusion criteria

Exclusion criteria: 1. Patients with complications of organic brain diseases other than the target disease 2. Patients with complications from serious diseases 3. Patients with claustrophobia 4. Patients with pacemakers or internal metal (brain clips, bolts, etc.) 5. Patients with tattoos (including artistic makeup) 6. Patients who are pregnant, may become pregnant, or are breastfeeding 7. Other patients who are judged by the principal investigator or sub-investigator to be unsuitable as subjects.

Design outcomes

Primary

MeasureTime frame
We will compare amyloid, tau, and oxidative stress images in patients with dementia and healthy controls to determine the specific distribution and pattern of PET ligands in neurodegenerative diseases, and to evaluate whether PET/MRI is a useful method for assessing the pathophysiology.

Countries

Japan

Contacts

Public ContactHidehiko Okazawa

University of Fukui Biomedical Imaging Research Center

okazawa@u-fukui.ac.jp0776-61-8491

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026