Analysis of functional changes in the central nervous system in post-COVID-19 syndrome

Analysis of functional changes in the central nervous system in post-COVID-19 syndrome - Analysis of functional changes in the central nervous system in post-COVID-19 syndrome

Status

Recruiting

Phases

Unknown

Study type

Observational

Source

JPRN

Registry ID

JPRN-UMIN000046087

Enrollment

Registered

2021-11-17

Start date

2021-11-17

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Post-COVID-19 syndrome

Interventions

None listed

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: post-COVID-19 syndrome patients Patients with fibromyalgia Patients with chronic fatigue syndrome Healthy subjects

Exclusion criteria

Exclusion criteria: SARS-CoV-2 persistent infection Complications of severe mental illness such as schizophrenia Alcohol or drug addiction left handed During pregnancy or lactation, Under 20 years old, over 70 years old Physical or psychological situations inappropriate for MRI imaging Morphological abnormal findings of the brain revealed by simple brain MRI

Design outcomes

Primary

Measure	Time frame
We analyze the time-series changes in the BOLD signal between any two regions for whole brain (voxel, ROI, network) in post-COVID-19 syndrome patients, and search for regions with different functional connectivity from healthy subjects.	—

Secondary

Measure	Time frame
We will compare the functional connectivity of the central nervous system for post-COVID-19 syndrome, chronic fatigue syndrome, and fibromyalgia patients.	—

Countries

Japan

Contacts

Public ContactTomohiko Aoe

Teikyo University Pain Center, Chiba Medical Center

tomohikoA@med.teikyo-u.ac.jp0436-62-1211

Outcome results