Evaluation of carbon dioxide production and oxygen demand using indirect calorimetry in patients with sepsis

Carbon dioxide production and oxygen uptake evaluated by indirect calorimetry in mechanically ventilated patients with sepsis - Indirect calorimetry in sepsis

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

JPRN

Registry ID

JPRN-UMIN000045966

Enrollment

100

Registered

2021-11-04

Start date

2019-01-01

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Sepsis

Interventions

None listed

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Adult patients with sepsis who required mechanical ventilation in the intensive care unit (ICU) were enrolled. Sepsis was diagnosed according to Sepsis-3.

Exclusion criteria

Exclusion criteria: Following patients were excluded because of the inaccuracy of indirect calorimetry (IC) measurement: patients complicated with pneumothorax, those treated with extracorporeal membrane oxygenation (ECMO) therapy, those ventilated with more than 85% fraction of inspired oxygen (FIO2), those with changes in ventilator settings during IC measurement, those intubated from nasal or tracheostomy, and those isolated for high risk of airborne infection. Moreover, we excluded patients who declared do not attempt resuscitation (DNAR) and those without informed consent.

Design outcomes

Primary

Measure	Time frame
28-day survival	—

Countries

Japan

Contacts

Public ContactIchiro Hirayama

The University of Tokyo Department of Emergency and Critical Care Medicine

ichirohirayama1983@gmail.com03-3815-5411

Outcome results