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Treatment-related mortality with Hematopoietic Stem Cell Transplantation for Progressive Systemic Sclerosis: A Systematic Review and Meta-Analysis

Treatment-related mortality with Hematopoietic Stem Cell Transplantation for Progressive Systemic Sclerosis: A Systematic Review and Meta-Analysis - Systematic review

Status
Active, not recruiting
Phases
Unknown
Study type
Unknown
Source
JPRN
Registry ID
JPRN-UMIN000045965
Enrollment
Unknown
Registered
2021-11-03
Start date
2021-11-05
Completion date
Unknown
Last updated
2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Systemic sclerosis

Interventions

None listed

Sponsors

Yokohama City University Graduate School of Medicine, Department of Stem Cell and Immune Regulation
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: (1) The published study including case-control study, cohort study, and randomized clinical trial. (2) The experimental group of the study was treated by HSCT, with or without control treatment arm. (3) The patients were clinically diagnosed with SSc. (5) The study illustrates the safety of HSCT. (6) Only full-text papers are used to analyze.

Exclusion criteria

Exclusion criteria: (1) Systematic review or meta-analysis articles. (2) Case reports or case series reporting less than 5 cases. (3) The republished research literature is excluded unless the research includes new findings related to adverse events listed in inclusion criteria. (4) Studies with no or insufficient safety results at the time of the literature search. (5) Studies published in languages other than English.

Design outcomes

Primary

MeasureTime frame
Overall survival

Secondary

MeasureTime frame
Treatment related death

Countries

Japan

Contacts

Public ContactKaoru Minegishi

Yokohama City University Graduate School of Medicine Department of Stem Cell and Immune Regulation

kaoru_t@yokohama-cu.ac.jp045-787-2630

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026